Final answer:
Sickle cell disease is a genetic disorder that can lead to various complications including rib infarction in children, due to the sickle-shaped red blood cells that block blood flow.
Step-by-step explanation:
Rib Infarction in a child with Sickle Cell Disease is possible. Sickle cell disease is a genetic disorder in which red blood cells become sickle-shaped and reduce oxygen perfusion into the blood. This abnormal shape can cause the cells to become lodged in capillaries, impeding blood flow and leading to various complications, such as rib infarction, which is the death of bone tissue due to a lack of blood supply. It is an autosomal recessive disorder caused by a mutation in the hemoglobin-Beta gene found on chromosome 11. The mutation affects hemoglobin in red blood cells, which leads to the sickle shape, especially under conditions of low oxygen.
This condition is particularly prevalent among people with African ancestry. The sickle-shaped cells can also lead to other serious health issues, including pain, swelling, tissue damage, and more severe conditions like stroke or blindness.