Final answer:
The management of GBS infection in an ill-appearing newborn involves prompt medical intervention, including administration of intravenous antibiotics for at least 10-14 days. Supportive care may also be provided as needed.
Step-by-step explanation:
In the case of an ill-appearing newborn with a GBS infection, the management involves prompt medical intervention. The first step is to obtain blood and cerebrospinal fluid (CSF) cultures to confirm the diagnosis. Once diagnosed, treatment typically includes administration of intravenous antibiotics, such as penicillin or ampicillin, along with an aminoglycoside antibiotic like gentamicin. The antibiotics are given for a duration of at least 10-14 days to effectively treat the infection. Supportive care, including fluid and oxygen therapy, may also be provided as needed.