Question

What is the interaction between IGF-1, GH, and Insulin?

1) They have no interaction
2) They have a synergistic interaction
3) They have an antagonistic interaction
4) Their interaction depends on the individual's health condition

Answer 1

IGF-1, GH, and Insulin have a synergistic interaction in promoting tissue growth and protein synthesis in the body.

Step-by-step explanation:

The interaction between IGF-1 (insulin-like growth factor 1), GH (growth hormone), and Insulin in the body is complex and interrelated. GH indirectly stimulates the production of IGF-1, which is responsible for promoting tissue growth and cellular proliferation. IGF-1, in turn, acts on cells to increase their uptake of amino acids from the blood, allowing the formation of new proteins in skeletal muscle cells and other target cells.

The release of GH is regulated by two hormones produced by the hypothalamus. GH release is stimulated by growth hormone-releasing hormone (GHRH) and is inhibited by growth hormone-inhibiting hormone (GHIH) or somatostatin.

In summary, IGF-1, GH, and Insulin have a synergistic interaction in promoting tissue growth and protein synthesis in the body.