Final answer:
Administer supplemental oxygen, bronchodilators, and possibly corticosteroids or antibiotics.
Step-by-step explanation:
For a 65-year-old male with a history of COPD experiencing severe shortness of breath, it is important to take immediate action. One approach is to administer supplemental oxygen to improve oxygen levels in the blood and alleviate symptoms. Additionally, the patient may benefit from bronchodilators, which help to relax the airway muscles and improve airflow. In severe cases, the use of corticosteroids or antibiotics may be necessary to reduce inflammation and treat any underlying infections.