Final answer:
The Montreal Protocol is the international agreement that regulated substances like CFCs to protect the ozone layer, with broad global participation and ongoing signs of ozone recovery.
Step-by-step explanation:
The international agreement that regulated the production and use of CFCs, HCFCs, Halons, methyl chloroform, and carbon tetrachloride is the Montreal Protocol. This treaty was specifically created to address the issue of the ozone hole in Earth's atmosphere. The Montreal Protocol on Substances that Deplete the Ozone Layer, commonly referred to as the Montreal Protocol, was established in 1987. It aimed to phase out the production and emission of 96 chemicals that were damaging the ozone layer, including CFCs, which have been mostly phased out since 1995. This global agreement has seen worldwide participation and has contributed to indicators of recovery in the ozone layer, though challenges remain.