Final answer:
Margaret Macdonald is the female nurse who started when most nurses were men. She succeeded Georgina Pope as Matron of the Canadian Army Nursing Service and played a significant role in organizing the nurses for the first Canadian overseas contingent.
Step-by-step explanation:
The female nurse who started when most nurses were men is Margaret Macdonald. She joined Georgina Pope in 1906 as the second nurse to receive a permanent appointment in the Canadian Army Medical Corps. When the First World War broke out, Macdonald was called from Kingston to Ottawa to succeed Pope as Matron of the Canadian Army Nursing Service. She played a key role in selecting and organizing the nurses required to staff the two general hospitals that accompanied the first Canadian overseas contingent.