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MHC proteins are involved in the recognition of self and non-self by the _______ system

a) Nervous
b) Immune
c) Endocrine
d) Muscular

User Saurjk
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1 Answer

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Final answer:

MHC proteins are crucial for the immune system, specifically for its ability to recognize self from non-self. They are presented by nucleated cells to T-cells, and abnormalities in MHC signaling can lead to autoimmune diseases.

Step-by-step explanation:

The correct option : b

The immune system employs MHC molecules to distinguish between self and non-self entities. MHC class I molecules are found on all nucleated cells and present peptides to T-cells, enabling the immune cells to monitor the health of these cells. If a cell is infected by a virus or becomes cancerous, MHC class I molecules will present abnormal peptides to T-cells, signaling an immune response. Meanwhile, MHC class II molecules are typically found on antigen-presenting cells and are involved in signaling between these cells and helper T-cells. These interactions are crucial for the immune response, leading to the activation of other immune cells and the production of antibodies.

A person who cannot produce MHC I molecules might develop an autoimmune disease, as their immune system would fail to recognize self cells correctly, potentially attacking healthy body cells.

User Bahrom
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