Question

A patient complains of new onset hematuria, left flank pain and unintentional weight loss. Her past medical history is significant for chronic hypertension and tobacco use. Abdominopelvic imaging reveals a mass within the confines of the left renal capsule. A surgical biopsy is taken. When considering the most common kidney cancer in adults, the histology report of this patient's biopsy would most likely describe abnormalities of which of the following cells?

a. Connective tissue cells of the renal stroma
b. Epithelial cells of the proximal convoluted tubule
c. Stromal cells of the metanephrogenic blastema
d. Transitional cells of the renal pelvis

Answer 1

The histology report of a patient with the most common adult kidney cancer typically shows abnormalities of the epithelial cells of the proximal convoluted tubule, indicating renal cell carcinoma.

Step-by-step explanation:

When considering the most common kidney cancer in adults, the histology report of this patient's biopsy would most likely describe abnormalities of the epithelial cells of the proximal convoluted tubule. This suggests that the patient could be suffering from renal cell carcinoma (RCC), which is the most common type of kidney cancer in adults and originates from the lining of the proximal convoluted tubule. The combination of hematuria, flank pain, and unintentional weight loss are classic symptoms, and the patient's smoking history and hypertension are risk factors for RCC.