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Beta-lactam antibiotics interfere with peptidoglycan synthesis. Based on this information, you can conclude the bacterial structure most likely targeted by these drugs is ____.

a) Cell Membrane

b) Nucleus

c) Cell Wall

d) Cytoplasm

User Pedrovgp
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Final answer:

Beta-lactam antibiotics target the cell wall of bacteria by disrupting the synthesis of peptidoglycan, which is essential for bacterial growth and protection, but not present in human cells.

Step-by-step explanation:

Beta-lactam antibiotics are specifically designed to interfere with the synthesis of peptidoglycan, which is a crucial component of bacterial cell walls. This complex molecule composed of polysaccharide chains cross-linked by peptides is vital for the bacteria's protection. Therefore, the bacterial structure most likely targeted by these drugs is c) Cell Wall.

The mechanism of these antibiotics involves mimicking D-amino acids to disrupt the cell wall development. For example, penicillins, which are a group of beta-lactam antibiotics, inhibit the transpeptidase cross-linking activity of penicillin-binding proteins, essential for cell wall synthesis.

As human cells do not possess peptidoglycan, targeting this process exhibits selective toxicity and is particularly effective against bacteria, making these antibiotics bactericidal.

User CXJ
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