Question

Briefly (but mention key points) describe the experiment Folkman conducted with the rat thyroid gland and what conclusion he drew from these studies.

A) Tested effects of growth factors; Inhibited tumor growth
B) Investigated hormone secretion; Identified genetic mutations
C) Explored tissue regeneration; Triggered cell differentiation
D) Studied blood vessel formation; Inhibited angiogenesis

Answer 1

Folkman experimented with the rat thyroid gland to study blood vessel formation and inhibited angiogenesis, finding that by inhibiting angiogenesis, he could effectively prevent tumor growth. The option (D) is correct.

Step-by-step explanation:

Folkman conducted an experiment with the rat thyroid gland to study blood vessel formation and inhibited angiogenesis, which is the process of forming new blood vessels. He found that by inhibiting angiogenesis, he could effectively prevent tumor growth.

This experiment demonstrated the importance of angiogenesis in tumor development and provided the basis for the development of anti-angiogenic therapies for cancer. Therefore, option (D) is correct.