Final answer:
General transcription factors bind at promoter regions and enhancers to facilitate gene expression; they bind at enhancers to increase and at silencers to decrease transcription.
Step-by-step explanation:
The correct option : a
General transcription factors play a foundational role in regulating gene expression by interacting with DNA at specific sites. The correct completion for the given statement is: General transcription factors bind at promoter regions and enhancers. They bind at enhancer regions of the DNA, which are distant from the gene, and increase transcription.
On the other hand, they bind at silencers and decrease transcription. General transcription factors bind at promoter regions and enhancers. They bind at promoter regions of the DNA, which are distant from the gene, and increase transcription. On the other hand, they bind at silencers and decrease transcription.