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For the transformations below, what is the structure of the major product?

OH-Br → DMF → ?

a) O-
b) O
c) O
d) OH
e) O

User Sirmak
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1 Answer

6 votes

Final answer:

e) O The primary transformation involves an SN2 reaction where hydroxide (OH-) substitutes a bromine atom (Br) to form an alcohol in the presence of DMF, a polar aprotic solvent conducive to SN2 reactions.

Step-by-step explanation:

The question relates to organic chemistry, specifically a substitution reaction involving halogens and an alcohol group in the presence of a solvent such as DMF (Dimethylformamide). The student is given a sequence of reagents (OH- and Br) and is asked to determine the major product of this transformation.

The options given suggest that the products are variations of an alcohol or an ether. To solve this, we should recall that OH- is a strong nucleophile and will substitute the Br atom to form a new alcohol group.

The reaction appears to be a simple halide substitution where the OH- replaces the Br, resulting in the formation of an alcohol. Since DMF is a polar aprotic solvent, it is often used in SN2 reactions, which proceed with inversion of configuration at the carbon atom bearing the leaving group.

Therefore, the major product is likely to be an alcohol with the OH group replacing the Br atom.

The major product in the given reaction sequence will have the structure (e) O.

The starting reactant OH-Br is an alkyl halide, which can undergo a substitution reaction with DMF (dimethylformamide), a strong polar aprotic solvent. This substitution reaction replaces the halogen (Br) with the DMF group.

The resulting product then undergoes elimination reaction by reacting with a base, and the major product formed has an oxygen atom (O) attached to the carbon atom where the halogen was originally located.

User Ramon Medeiros
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