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Following S phase, a human cell would have how many pairs of sister chromatids and individual DNA molecules?

a. 23 pairs of sister chromatids, 23 individual DNA molecules
b. 46 pairs of sister chromatids, 23 individual DNA molecules
c. 23 pairs of sister chromatids, 46 individual DNA molecules
d. 46 pairs of sister chromatids, 46 individual DNA molecules

User Tyrice
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1 Answer

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Final answer:

After the S phase, a human cell contains 46 pairs of sister chromatids and 92 individual DNA molecules, as each of the 46 chromosomes duplicates into two chromatids attached at the centromere.

Step-by-step explanation:

The correct option : d

During the S phase, each of the 46 chromosomes is replicated, forming two identical chromatids. These sister chromatids stay attached to each other at their centromere through proteins known as cohesins. As a result, after the S phase and before cell division, there are a total of 92 chromatids present in a cell, accounting for 46 pairs since each chromosome now consists of two chromatids.

The term "pair of sister chromatids" refers to the two identical halves of a single replicated chromosome, while "individual DNA molecules" pertains to each chromatid bearing a DNA molecule. It is essential not to confuse sister chromatids with a homologous pair of chromosomes, which are two different chromosomes inherited from each parent.

User Frankish
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