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Which non-selective b-receptor antagonist has intrinsic sympathomimetic activity?

a) Timolol
b) Pindolol
c) Betaxolol
d) Carteolol

User Monofal
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1 Answer

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Final answer:

Pindolol is the non-selective β-receptor antagonist with intrinsic sympathomimetic activity, distinguishing it from other β-blockers by its ability to partially activate β-receptors while blocking adrenaline's full effects.

Step-by-step explanation:

The non-selective β-receptor antagonist with intrinsic sympathomimetic activity is Pindolol.

β-blockers are a type of sympatholytic drug used in the treatment of cardiovascular diseases. They work by blocking the effects of adrenaline on the β-receptors associated with vasoconstriction and cardioacceleration. This action helps in dilating blood vessels and preventing increases in heart rate, thus improving cardiac function.

Non-selective β-blockers like propranolol bind to all β-receptors, while selective ones, like metoprolol, target β1-receptors specifically. Pindolol is unique among β-blockers because it not only blocks the β-receptors but also has intrinsic sympathomimetic activity, meaning it can partially activate β-receptors while blocking the full effects of naturally occurring sympathetic neurotransmitters like adrenaline.

User Ataraxic
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