Question

Two ways a-2 agonists reduce production of aqueous humor.

a) Reduce cAMP production
b) Increase cAMP production
c) Ciliary vasoconstriction and decreased ciliary blood flow
d) Increased aqueous humor secretion

Answer 1

α-2 agonists reduce production of aqueous humor by reducing cAMP production and causing ciliary vasoconstriction and decreased ciliary blood flow.

Step-by-step explanation:

Two ways that α-2 agonists reduce production of aqueous humor are:

1. Reduce cAMP production: α-2 agonists bind to α-2 adrenergic receptors on the ciliary epithelium, which decreases the production of cyclic adenosine monophosphate (cAMP). This inhibits the production of aqueous humor.
2. Ciliary vasoconstriction and decreased ciliary blood flow: α-2 agonists also cause vasoconstriction in the ciliary body, reducing blood flow to the ciliary processes. This decreases the production of aqueous humor.