Final answer:
The most similar peptide to spHM FLGFTY that would likely achieve the same experimental results is FLGFGY (option C), due to the substitution of similar amino acids that maintain the peptide's properties.
Step-by-step explanation:
The question you are asking relates to peptide similarity and how substitution of certain amino acids may affect the functionality of a peptide.
In the context of the peptide spHM FLGFTY, we are looking for a substitute peptide that would most likely yield the same experimental results.
The most crucial factor in maintaining peptide function is the conservation of properties of the amino acid side chains.
When we compare the peptides given as options, the peptide sequence FLGFGY (option C) is the most similar to the original sequence spHM FLGFTY, with only a single amino acid difference where serine (S) is substituted by glycine (G), both of which are small and relatively neutral amino acids.
Thus, they are more likely to maintain a similar structure and function.