Question

The runner has a masculinized brain, was born with female genitalia, although male chromosomes XY, she can't convert testosterone into DHT, this is a hormonal case

A) Turner Syndrome
B) Klinefelter Syndrome
C) Swyer Syndrome
D) 5-alpha Reductase Deficiency

Answer 1

5-alpha Reductase Deficiency is the hormonal case described in the question, where a person has XY chromosomes but is unable to convert testosterone into dihydrotestosterone (DHT). This condition can lead to ambiguous genitalia and impact fertility.

Step-by-step explanation:

The hormonal case described in the question is known as 5-alpha Reductase Deficiency. This condition is characterized by the inability to convert testosterone into dihydrotestosterone (DHT). People with 5-alpha Reductase Deficiency are typically assigned female at birth due to the presence of female genitalia, but they have XY chromosomes.

Due to the lack of DHT, individuals with this condition may develop masculine characteristics during puberty. However, the external genitalia may remain female-like.

Some individuals with 5-alpha Reductase Deficiency may have ambiguous genitalia, and the condition can impact fertility. Hormone replacement therapy may be used to manage the hormonal imbalances associated with this condition.