Final answer:
Sadness is a manifestation of compassion fatigue, which is a type of burnout that affects caregivers due to the heavy emotional and physical demands of their work.
Step-by-step explanation:
A nurse caring for hospice clients and experiencing compassion fatigue may manifest several symptoms, and among the options provided, sadness is a common manifestation of compassion fatigue. Compassion fatigue can be described as a form of burnout that occurs due to the emotional and physical demands of caring for patients, particularly in settings that deal with death and serious illness, such as hospice care. Other signs include emotional exhaustion, a decrease in empathy, irritability, and trouble concentrating. Increased intimacy and mistrust are not typically associated with compassion fatigue.