Answer: Acetaminophen.
Explanation: The drug that is most commonly known to cause liver failure is acetaminophen, which is commonly found in over-the-counter pain medications such as Tylenol. Acetaminophen is a commonly used pain reliever and fever reducer, but it can cause liver failure when taken in high doses or when combined with alcohol.
If a client with multiple pain-related injuries to the back, knees, and hips is admitted with acute liver failure and is taking several over-the-counter medications that contain acetaminophen, it is possible that the acetaminophen could have contributed to their liver failure. In this situation, it is important for the nurse to carefully review the client's medication list and to monitor their liver function closely. The nurse may need to adjust the client's medications or provide liver-protective therapies to help prevent further liver damage.