Question

As Devon was researching Tay Sachs disease, his brother called to tell him that his nephew was improving, and doctors were optimistic that his condition was not as serious as they had initially indicated. Devon was relieved and couldn't help but think about all the families that were not fortunate enough to hear such good news. He returned to reading about how Tay Sachs results in lysosomes filling up with fatty material that damages and eventually kills cells of the nervous system--ultimately resulting in death by age 4. He surprised himself by realizing he was able to visualize the normal process by which a lysosome would form. Which of the following best describes normal lysosomal development?

A) Fusion with Endosomes
B) Autophagy
C) Hydrolysis of Substrates
D) Exocytosis

Answer 1

Normal lysosomal development most accurately reflects the formation and release of enzyme-containing vesicles by the Golgi apparatus, which may then become new lysosomes or fuse with existing ones, facilitating the process of autophagy.

Step-by-step explanation:

Normal lysosomal development involves the process where the enzyme-containing vesicles released by the Golgi apparatus may form new lysosomes, or fuse with existing lysosomes. Lysosomes are crucial organelles that contain enzymes to break down and digest unneeded cellular components, such as damaged organelles. This process is known as autophagy, and it's crucial for cellular health and maintenance. The fusion with endosomes is a significant aspect of lysosomal function, but when considering the entire development process of a lysosome, the formation and release of enzyme-containing vesicles by the Golgi is most indicative of normal development.