Question

What is the most common primary immunodeficiency, and what are its characteristic features?

a) Common variable immunodeficiency (CVID)
b) X-linked agammaglobulinemia (XLA)
c) Wiskott-Aldrich syndrome
d) Severe combined immunodeficiency (SCID)

Answer 1

The most common primary immunodeficiency is common variable immunodeficiency (CVID), which is characterized by frequent bacterial infections, low levels of immunoglobulins, variable age of onset and presentation, and increased risk of autoimmune diseases.

Step-by-step explanation:

The most common primary immunodeficiency is common variable immunodeficiency (CVID).
Characteristic features of CVID include:

• Frequent and severe bacterial infections, especially in the respiratory system
• Low levels of immunoglobulins (antibodies) in the blood
• Variable age of onset and clinical presentation
• Increased risk of autoimmune diseases, such as autoimmune thrombocytopenia or rheumatoid arthritis