Final answer:
The keyboard shortcut to return to cell A1 in Microsoft Excel and similar spreadsheet programs is Ctrl + Home.
Step-by-step explanation:
The keyboard shortcut that will automatically return you to cell A1 in spreadsheet programs such as Microsoft Excel is Ctrl + Home. When you press this combination of keys, the spreadsheet will instantly navigate back to the beginning of the document, which is cell A1. This is a useful shortcut for quickly getting back to the start of your data without having to scroll manually.