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Prozac and similar drugs work to reduce depression by _____.

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Final answer:

Prozac, an SSRI, works by blocking the reuptake of serotonin into the presynaptic neuron, increasing serotonin levels in the synaptic cleft to help improve mood in those with depression.

Step-by-step explanation:

Prozac and similar drugs work to reduce depression by blocking the reuptake of serotonin into the presynaptic neuron. These drugs, known as Selective Serotonin Reuptake Inhibitors (SSRIs), increase the amount of serotonin in the synaptic cleft, which is thought to contribute to elevated mood and reduced symptoms of depression. Common SSRIs on the market include Prozac, Zoloft, and Paxil. Prozac acts as a serotonin reuptake inhibitor, not an agonist or antagonist, by preventing the neurotransmitter from being taken back into the neuron after it has been released into the synaptic cleft. This mechanism gives serotonin more time to act on its receptors on dendrites, potentially improving mood in individuals with depression.

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