Final answer:
ICF syndrome and Roberts syndrome are associated with abnormalities in chromosomal cohesion and gene expression. While ICF syndrome involves DNA methylation and histone modifications, Roberts syndrome involves a gene necessary for proper chromosomal separation during cell division. CF involves a different gene affecting chloride ion transport.
Step-by-step explanation:
ICF syndrome and Roberts syndrome are inherited diseases associated with abnormal chromosomal cohesion and gene expression. To clarify, ICF syndrome stands for Immunodeficiency, Centromeric instability, and Facial anomalies syndrome, and it is linked with dysfunctional DNA methylation and histone modifications.
In contrast, Roberts syndrome is related to impairments in ESCO2, a gene that is crucial for proper sister chromatid cohesion during cell division.
Cystic fibrosis (CF), mentioned in the context of this question, is another inherited condition, but it is distinct from the ICF and Roberts syndromes. CF is caused by a mutation in the CFTR gene, which leads to the production of a defective membrane ion channel, affecting chloride ion transport. This mutation results in thick, sticky mucus that can clog various organs.