Final answer:
Many African Americans moved northward in the early 20th century as part of the Great Migration, with a significant number settling in Harlem, which became a center for African American culture.
Step-by-step explanation:
In the early 20th century, during the Great Migration, many African Americans moved northward seeking opportunities for economic advancement, jobs, education, and a more tolerant environment. While they settled in cities across the North and West, many found their way to a significant destination known as Harlem, located in New York City. Harlem became an influential center for African American cultural growth and expression, eventually leading to the blossoming of the Harlem Renaissance.