Final answer:
The MIBG scan is an isotope scan that targets the adrenal glands for the purpose of imaging certain types of tumors such as neuroblastoma and pheochromocytoma.
Step-by-step explanation:
The MIBG scan is a specific type of isotope scan used to identify a problem with the adrenal glands.
MIBG, or metaiodobenzylguanidine, is a radiopharmaceutical used in nuclear medicine to visualize certain types of tumors, particularly those affecting the adrenal glands, such as neuroblastoma and pheochromocytoma. These tumors are typically associated with the adrenal medulla, the inner part of the adrenal glands which produce adrenaline-like substances. The MIBG compound resembles noradrenaline and thus is taken up by neuroendocrine cells.
When labeled with a radioactive isotope, it allows imaging of the sympathetic nervous system and tissues that uptake catecholamines. This is especially valuable for diagnosing and localizing tumors that originate from or involve neural crest cells, which give rise to the aforementioned parts of the adrenal gland and other similar tissues.