Question

While reviewing a pathophysiology chapter on cell proliferation and tissue repair, the study group notices that the transition from G2 to M in the cell cycle is an important checkpoint and requires which proteins to be available to complete the process? Select all that apply.

a) Cyclin
b) Kinase
c) Ribosome
d) Hemoglobin

Answer 1

The G2/M checkpoint in the cell cycle requires cyclin and kinase proteins.

Step-by-step explanation:

The transition from G2 to M in the cell cycle is an important checkpoint known as the G2/M checkpoint. This checkpoint ensures that all of the chromosomes have been replicated and that the replicated DNA is not damaged. The proteins required to complete this process are:

• Cyclin: Cyclin proteins fluctuate throughout the cell cycle and regulate cell transitions through the various checkpoints.
• Kinase: Cyclin-dependent kinases (Cdks) are protein kinases that, when fully activated, can phosphorylate and activate other proteins to advance the cell cycle past a checkpoint.