Final answer:
The key to early disease detection lies in identifying changes in gene expression and metabolism when they become evident. Techniques like genome analysis help predict disease risk. Understanding gene expression mechanisms allows for better intervention strategies.
So, the correct answer is 2) evident.
Step-by-step explanation:
The key to detecting subtle changes in gene expression and metabolism before they become manifest as illness is recognizing them when they become evident. This can be achieved through methods like genome analysis, metabolomics, and proteomics, which help in predicting disease risk at the individual level.
Particularly, diseases like cancer can be seen as a result of altered gene expression, with detectable changes across several levels of gene regulation. It's crucial to understand these mechanisms in non-diseased cells to grasp what goes awry in disease states. Certain diseases may also be asymptomatic or subclinical, lacking noticeable signs or symptoms, further emphasizing the importance of early detection.
Understanding gene regulation and expression is critical in the potential prediction and intervention of diseases, such as cancer. Changes in DNA or RNA sequences can lead to variations in gene expression, which can result in diseases manifesting differently across individuals. Researchers look for epigenetic regulation changes, transcription variations, and other cellular processes that could indicate the onset of disease.
So, the correct answer is 2) evident.