Question

Mycolic acids are targeted by isoniazid in the treatment of which of the following?

1) S. aureus
2) S. epidermidis
3) M. luteus
4) M. tuberculosis
5) coli

Answer 1

Isoniazid is used to target mycolic acids in the treatment of tuberculosis caused by Mycobacterium tuberculosis. Option 4.

Step-by-step explanation:

The mycolic acids are targeted by the drug isoniazid in the treatment of Mycobacterium tuberculosis, which is the causative agent of tuberculosis. This bacterium is characterized by a waxy coat of mycolic acids that protect it from desiccation, certain antibiotics, and inhibits Gram staining.

This is why the acid-fast staining is used to visualize these bacteria. Isoniazid is an antimetabolite used in combination with other drugs to treat tuberculosis; it inhibits the synthesis of mycolic acids and is effective only against mycobacteria like M. tuberculosis.

So Option 4.