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What are three things to keep in mind in regards to the phosphate found in DNA?

User Hizzy
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Final answer:

The phosphate in DNA is part of the backbone structure, provides directionality, and has acidic properties affecting DNA's stability and interactions.

Step-by-step explanation:

When studying the phosphate found in Deoxyribonucleic Acid (DNA), there are three things to keep in mind:

  1. The phosphate group bonds covalently with the sugar molecule of the next nucleotide to form the sugar-phosphate backbone, which is essential for the structure and integrity of DNA.

  2. The phosphate is attached to the 5' carbon of one nucleotide and the 3' carbon of the next nucleotide, giving DNA its directionality (5' to 3' and 3' to 5' anti-parallel strands).

  3. Phosphate groups in DNA have acidic properties, with phosphodiester bonds between nucleotides having pKa values from 1 to 3, influencing DNA stability and interactions with other molecules.

User Ejez
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