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What are the consequences of pericentric inversions of a heterozygote during meiosis?

User Harukaeru
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Final answer:

During meiosis, the consequence of a pericentric inversion in one homologous chromosome and a normal homolog is the formation of a loop in one homolog and the molding around it by the other homolog. This maintains point-for-point synapsis and correct gene alignment but may lead to stretching and imprecise synapsis in certain regions.

Step-by-step explanation:

During meiosis, when one homologous chromosome undergoes a pericentric inversion (which includes the centromere), while the other remains normal, the individual is considered an inversion heterozygote. To pair accurately along their lengths, the homologs assume a specific structure.

One homolog forms a loop and the other homolog molds around it during point-for-point synapsis. Although this ensures correct gene alignment, it also forces the homologs to stretch and can be associated with regions of imprecise synapsis.

User Cesarsotovalero
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