Question

What type of chromosomal mutation would result in the following chromosome rearrangement: STXYUV⋅WXYZ?

1) Deletion
2) Tandem Duplication
3) Displaced Duplication
4) Reverse Duplication
5) None of the Above

Answer 1

A Displaced Duplication mutation results in the chromosome rearrangement STXYUV⋅WXYZ, where a segment is duplicated and inserted into a non-adjacent location on the chromosome.

Step-by-step explanation:

The chromosomal mutation that would result in the chromosome rearrangement STXYUV⋅WXYZ is best described as a Displaced Duplication. This type of mutation involves the duplication of a chromosome segment followed by its integration at a non-adjacent site on the chromosome.

In this case, the segment 'WXYZ' is duplicated from its original location and inserted after 'UV', resulting in the new arrangement. It is not a deletion, as no segment is lost; it's not a tandem duplication since the duplicated segment isn't adjacent to its original location; and it's not a reverse duplication because the sequence isn't reversed.

Answer 2

The chromosome rearrangement STXYUV⋅WXYZ indicates a chromosomal mutation known as a displaced duplication, where a segment is copied and inserted at a non-adjacent location within the chromosome.

Step-by-step explanation:

The question asked is related to a particular type of chromosomal mutation that would cause a specific rearrangement of chromosome segments, resulting in the pattern STXYUV⋅WXYZ. Looking at the typical outcomes of different chromosomal mutations, a deletion removes a segment, tandem duplication copies a segment and places it adjacent to the original, displaced duplication copies a segment and inserts it at another location on the same or different chromosome, and a reverse duplication also involves copying a segment but with an inversion or reverse orientation of the duplicated segment.

The given sequence STXYUV⋅WXYZ does not indicate a simple deletion or a tandem duplication, as the original sequence is not adjacent. It does suggest that a segment has been copied and rearranged. Since the 'WXYZ' sequence is not in reverse orientation, this rules out a reverse duplication. This leaves us with displaced duplication, where the 'WXYZ' segment has been duplicated and inserted into another location in the chromosome. Thus, the correct option for the chromosomal mutation resulting in the pattern STXYUV⋅WXYZ is a displaced duplication.

Therefore, the correct answer to the question is: 3) Displaced Duplication.