Question

Chronic hepatitis B viral infection in the immune-active, hepatitis B e antigen-positive phase should be treated with ___ or ___ to decrease hepatic inflammation and the risk for progression to fibrosis.

1) Antiviral therapy
2) Liver transplantation
3) Immunosuppressive drugs
4) Blood transfusion

Answer 1

To treat chronic hepatitis B in the immune-active phase, antiviral therapy is recommended to minimize liver damage and prevent fibrosis.

Step-by-step explanation:

Chronic hepatitis B viral infection in the immune-active, hepatitis B e antigen-positive phase should be treated with antiviral therapy to decrease hepatic inflammation and the risk for progression to fibrosis.

Treatments such as interferon alpha 2b and antivirals like lamivudine, entecavir, adefovir, and telbivudine are specifically used for managing chronic hepatitis B infections.

While liver transplantation may be a consideration in severe cases, for the immune-active phase of the disease, the focus is on medical management with antiviral agents rather than surgical intervention or other therapies such as immunosuppressive drugs or blood transfusion, which are not typically used in this context.