Final answer:
An excess of acid phosphatase can lead to conditions such as metabolic acidosis, hyperphosphatemia, hypocalcemia, renal rickets, and gout or Von-Gierke's disease due to uric acid accumulation.
Step-by-step explanation:
Explanation in 200 words: Acid phosphatase is an enzyme significant in various physiological processes, but its excess can result in several pathological conditions. For instance, an overabundance of acid phosphatase can contribute to metabolic acidosis, which develops when the body accumulates too many acids such as sulfates, phosphates, or uric acid. This can negatively impact enzyme activity and increase the excitability of cardiac and neural membranes. Furthermore, high acid levels can lead to hyperphosphatemia, where the blood has abnormally high phosphate levels, concurrently causing hypocalcemia, or abnormally low calcium levels in the blood.
These imbalances can promote the formation of calcium phosphate stones in organs like the kidneys. Rickets, often associated with vitamin D deficiency, can also manifest with high acid phosphatase activity, leading to skeletal deformities due to improper bone calcification. Lastly, conditions such as Von-Gierke's disease are characterized by an overproduction of uric acid due to metabolic disturbances, which can precipitate conditions like gout, resulting from excessive tissue destruction.