Final answer:
Vital Capacity (VC) is the largest normal lung volume measurement, as it combines expiratory reserve volume, tidal volume, and inspiratory reserve volume.
Step-by-step explanation:
The lung volume measurement that is normally the largest is Vital Capacity (VC). VC refers to the maximum amount of air that can be inhaled or exhaled during a respiratory cycle.
It is the sum of three components: expiratory reserve volume (ERV), tidal volume (TV), and inspiratory reserve volume (IRV).
The inspiratory reserve volume is specifically the additional amount of air that can be inhaled after a normal inhalation. Neither Inspiratory reserve volume, Functional residual capacity, nor Residual capacity alone constitutes the largest measurement when compared to Vital Capacity, as VC integrates multiple volumes for its total measurement.