Final answer:
The Anasazi, or Ancient Puebloans, differentiated themselves from similar cultures with their advanced architecture, such as multi-storied buildings and cliff dwellings, their agricultural practices, especially in corn cultivation and storage, and their extensive trade networks.
Step-by-step explanation:
The Anasazi culture, also known as the Ancient Puebloans, set itself apart from other similar cultures in the region through several distinctive practices and architectural achievements. They inhabited the Four Corners region from around 700-1300 CE, where they produced large, multi-storied apartment-like buildings and kivas, which were ceremonial centers. The incorporation of multi-story complexes carved into cliff faces, such as those at Mesa Verde, and their advanced agricultural practices, specifically the cultivation and storage of corn, are hallmark features that differentiate the Anasazi from other Southwest pueblo cultures. Their extensive trade networks, which included luxury items from distant regions, and their advanced pottery are also noteworthy traits of the Anasazi culture.