Final answer:
The nurse should instruct the client to take methylprednisone with food to minimize stomach upset.
Step-by-step explanation:
The nurse should include the following instruction: 1) Take the medication with food to minimize stomach upset.
Methylprednisone is a corticosteroid medication commonly prescribed for multiple sclerosis. Taking it with food can help prevent stomach irritation that may occur as a side effect.
The other options mentioned - avoiding sunlight, stopping the medication due to side effects, and taking the medication at bedtime for sleep - are not specifically recommended for methylprednisone use in multiple sclerosis. It is important for the nurse to provide accurate and specific instructions to the client.