Final answer:
Identification of metastatic properties involves analyzing gene expression patterns, utilizing metabolomics and proteomics to study gene-produced metabolites and biomarkers, and detecting abnormal glycoproteins that promote cancer cell detachment and migration.
Step-by-step explanation:
Three key factors that led to the identification of metastatic properties to identify differentially expressed candidate genes are the understanding of gene expression patterns, the use of metabolomics and proteomics, and the detection of abnormal cell surface glycoproteins. First, by studying gene expression patterns, researchers can identify faulty genes responsible for cancer and thereby facilitate targeted drug treatment.
Second, metabolomics helps in analyzing the metabolites produced by genes during cancer progression, while proteomics is instrumental in detecting biomarkers affected by the disease process. Lastly, abnormal cell surface glycoproteins promote the detachment of cancer cells from the primary tissue and their migration to other parts of the body, a process known as metastasis. Through these methods, researchers can better understand the biological changes occurring in carcinomas and identify cancer-specific genetic alterations.