Question

In stage 3 of fatty acid synthesis, synthesis continues until _________ is formed, which is cleaved by _______ to yield _______.

Answer 1

In stage 3 of fatty acid synthesis, synthesis progresses until palmitoyl-ACP is formed, which is then hydrolyzed by the enzyme hydrolase to produce palmitate. This process involves seven cycles of reactions in the FAS complex and uses NADPH as a reducing agent.

Step-by-step explanation:

In stage 3 of fatty acid synthesis, synthesis continues until palmitoyl-ACP is formed, which is cleaved by hydrolase to yield palmitate. Fatty acid synthesis involves a cyclic series of reactions that take place in the fatty acid synthase (FAS) complex. This process is repeated through seven turns to produce a 16-carbon fatty acid chain. Upon completion, palmitoyl-ACP is hydrolyzed by the enzyme hydrolase to release palmitate, which is immediately converted to palmitoyl-CoA in the cell. The biosynthesis pathway for fatty acids is highly regulated and uses different enzyme systems from those found in the degradation pathway, with each turn of the cycle in fatty acid synthesis using NADPH as a reducing agent.