Final answer:
A vesicle from the Golgi apparatus or ER integrates with the plasma membrane by fusing with it, turning its inside face into the membrane's outer face. The Golgi apparatus modifies and sorts proteins and lipids, which are then transported to their destinations, including the cell surface.
Step-by-step explanation:
When a vesicle budded off from the Golgi apparatus or the Endoplasmic Reticulum (ER) fuses with the plasma membrane, the inside face of the vesicle becomes the outer face of the plasma membrane. This process is essential for the transportation of proteins and lipids within the cell and their delivery to various parts including the cell surface. The Golgi apparatus plays a pivotal role in this transport and modification system. It has a cis face, which is the receiving side, and a trans face, which is the releasing side.
The transport vesicles originating from the ER move towards the cis face, fuse with it, and their contents are released into the lumen of the Golgi apparatus. As they move through the Golgi apparatus, proteins and lipids are modified, commonly by the addition of short chains of sugar molecules, a process termed glycosylation. These modifications help in sorting and signaling, directing these molecules to their correct destination. The final step involves the vesicles that bud off from the trans face of the Golgi apparatus. These vesicles then proceed to the plasma membrane or other organelles, fusing with them and integrating their contents into the target membranes.