Final answer:
Dependovirus or Adeno-associated virus (AAV) requires a helper virus like Adenovirus for replication because it lacks the necessary genes for the replication machinery and borrows proteins from the helper virus.The AAV relies on the host cell's replication proteins, directed by the DNA from the helper virus, to synthesize new copies of its genome.
Step-by-step explanation:
The Dependovirus, also known as Adeno-associated virus (AAV), is a type of virus that requires another virus, known as a helper virus, for replication. AAV is unable to replicate on its own in the host cell and depends on the presence of a helper virus such as Adenovirus or Herpes simplex virus for the provision of essential proteins required for its replication process. This relationship is necessary because AAV lacks the genes that encode the replication machinery and thus borrows these proteins from the helper virus to facilitate its own replication.
During co-infection with a helper virus like Adenovirus, the AAV integrates its DNA into the host cell's genome and, using the helper virus's proteins, expresses its genes to produce new viral particles. The AAV relies on the host cell's replication proteins, directed by the DNA from the helper virus, to synthesize new copies of its genome. These new viral genomes are then packaged into capsids to form progeny virions, releasing them to infect new cells.