Final answer:
The statement that sister chromatids are held together by cohesins from the time they replicate until they separate at anaphase is true. Cohesin proteins bind the chromatids together at the centromere, ensuring proper chromosome segregation during cell division.
Step-by-step explanation:
The statement is: Sister chromatids are held together by cohesins from the time they arise by DNA replication until the time they separate at anaphase. This statement is True.
During the S phase of interphase, each chromosome duplicates, creating two identical sister chromatids. These chromatids are held together at a region known as the centromere by cohesin proteins. The key role of the cohesin proteins is to ensure that the sister chromatids remain connected through various cell cycle stages, including metaphase, where they line up at the metaphase plate. Cohesin proteins are important for the proper segregation of the chromatids during cell division.
At the onset of anaphase, cohesin proteins degrade, allowing the sister chromatids, which are now individual chromosomes, to separate and move towards opposite poles of the cell. This ensures that each new cell will receive the correct number of chromosomes during cytokinesis, the physical process of cell division.