Question

Given a pedigree chart with some individuals showing a disease manifestation predict the likelihood (probability) of an individual in a specific generation having the disease phenotype

A. if caused by a recessive allele, an individual must inherit two copies of the mutant allele to express the disease
B. two heterozygous will have 1/4 recessive or affected
C. all offspring are affected if parents are both affected

D. If dominantly caused, predicts that affected person will inherit the gene from at least one parent

Answer 1

The likelihood of an individual having a disease phenotype depends on the mode of inheritance, whether it is recessive or dominant. If caused by a recessive allele, an individual must inherit two copies of the mutant allele. If caused by a dominant allele, an affected person will inherit the gene from at least one parent.

Step-by-step explanation:

The likelihood of an individual in a specific generation having a disease phenotype depends on the mode of inheritance.

If the disease is caused by a recessive allele, the individual must inherit two copies of the mutant allele to express the disease. In this case, if both parents are heterozygous for the recessive allele, there is a 1/4 (25%) chance for each of their children to be affected by the disease.

If the disease is caused by a dominant allele, an affected person will inherit the gene from at least one parent. In this case, the likelihood of an individual in a specific generation having the disease phenotype depends on whether or not their parents are affected.

It's important to keep in mind that these probabilities are based on Mendelian inheritance patterns and assume no other complicating factors or genetic variations.