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Which of the following is the strongest interaction?

a. hydrogen bond
b. hydrophobic effect
c. ionic bond
d. phosphoanhydride bond
e. Van der Waals interaction

User Viki
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1 Answer

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Final answer:

Among hydrogen bond, hydrophobic effect, ionic bond, phosphoanhydride bond, and Van der Waals interaction, the phosphoanhydride bond is the strongest. Ionic bonds are stronger than hydrogen bonds and Van der Waals interactions, but both ionic and covalent bonds trump them in terms of strength.

Step-by-step explanation:

The question asks which of the following is the strongest interaction among hydrogen bond, hydrophobic effect, ionic bond, phosphoanhydride bond, and Van der Waals interaction. To address this, it is important to consider the strength of these interactions in a biological context. For the listed options, phosphoanhydride bonds (as found in ATP molecules), generally involve the largest energy changes upon hydrolysis and are considered the strongest among these options. Covalent bonds are stronger than ionic bonds, but the hydrophobic effect and Van der Waals interactions are generally weaker than hydrogen bonds. Our focus here is on molecular interactions often encountered in biological systems, particularly as they pertain to macromolecules like proteins and nucleic acids.

Ionic bonds form when an electron is transferred from one atom to another, leading to attraction between positively and negatively charged ions. While strong, these are typically weaker than covalent bonds, which involve the sharing of electrons between atoms. However, both ionic and covalent bonds are stronger than hydrogen bonds and Van der Waals interactions, which are considered types of non-covalent or intermolecular interactions. Hydrogen bonds, while weaker than ionic and covalent bonds, are still stronger than Van der Waals interactions, which include London dispersion forces and are the weakest of all intermolecular interactions.

The hydrophobic effect is not a direct interaction but rather an indirect consequence of nonpolar molecules aggregating to minimize their exposure to water, driven by the entropy of water molecules.

User Mats Ekberg
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