Question

The adaptive immune system uses multiple strategies to generate diversity in our ability to mount responses to a wide array of infectious microorganisms. These strategies include the generation of diverse repertoires of B-cell and T-cell antigen receptors, as well as polymorphism of MHC genes. The polymorphism of MHC genes differs from the diversity of lymphocyte antigen receptors in that:

A. It involves DNA rearrangements at multiple gene segments in the MHC locus.
B. It requires different enzymes than the RAG1/RAG2 recombinase required for
antigen receptor rearrangements.
C. It results in a diverse repertoire of clonally distributed receptors on dendritic cells,
rather than on lymphocytes.
D. It creates diversity between individuals in the population rather than within a
single individual.
E. It does not contribute to the transplant rejection responses that occur after organ
transplantation between unrelated individuals.

Answer 1

The polymorphism of MHC genes differs from the diversity of lymphocyte antigen receptors in that it creates diversity between individuals in the population, rather than within a single individual.

Step-by-step explanation:

The diversity of the MHC genes in the adaptive immune system differs from the diversity of lymphocyte antigen receptors in several ways. The polymorphism of MHC genes involves multiple alleles for each individual MHC locus, creating diversity between individuals in the population. On the other hand, the diversity of lymphocyte antigen receptors is achieved through the generation of diverse repertoires of B-cell and T-cell antigen receptors by DNA rearrangements. This leads to a diverse repertoire of clonally distributed receptors on lymphocytes, rather than on dendritic cells.