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What is the function of RNAP Wall?

A. Blocks exit of the nascent RNA transcript

B. Causes DNA bend; bending of DNA helps melt the strands and flip bases in the template strand to be accessible

C. Protects first nucleotides as they form the first phosphodiester bond

D. Helps stabilize double-stranded DNA structure

User Marimaf
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Final answer:

The RNAP wall function related to transcription is to cause DNA bending, facilitating the melting of DNA strands and making the template strand bases accessible for RNA synthesis (Option B).

Step-by-step explanation:

The function of the RNAP wall is not to synthesize RNA primers, hold DNA polymerase in place, relieve stress on DNA strands, or bind to single-stranded DNA. Instead, its role is associated with the process of RNA polymerase functioning during transcription. Given the options provided, the most accurate description for the RNAP wall's function is option B: Causes DNA bend; bending of DNA helps melt the strands and flip bases in the template strand to be accessible. This bending is crucial as it facilitates the opening of the DNA double helix, allowing RNA polymerase to read the template strand and synthesize the RNA transcript.

DNA replication and RNA transcription involve a variety of enzymes and factors, each with distinct functions. For example, helicase is responsible for separating DNA strands during replication, while single-strand binding proteins prevent the strands from reannealing. During transcription termination, a rho-independent mechanism involves a stable hairpin structure formed by specific sequences of the DNA template that stalls the RNA polymerase, eventually leading to the release of the RNA transcript as described in the additional information provided.

User Jovs
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