Question

Which of the following statements are TRUE regarding 'Polarity' in terms of bacterial gene expression?

A. Polarity occurs when all coding regions of a polycistronic transcript are experiencing heavy ribosome traffic.

B. It is when termination in a coding region located near the 5-end of a polycistronic mRNA causes the loss of both transcriptional and translational expression of all genes that follow it.

C. All of the coding regions have the same orientation to form a polycistronic mRNA.

D. It occurs when a rho-dependent terminator is located in the coding region of the last gene in a polycistronic mRNA.

Answer 1

b. Polarity occurs when termination in a coding region located near the 5-end of a polycistronic mRNA causes the loss of both transcriptional and translational expression of all genes that follow it.

Step-by-step explanation:

Statement B is TRUE regarding 'Polarity' in terms of bacterial gene expression. Polarity occurs when termination in a coding region located near the 5-end of a polycistronic mRNA causes the loss of both transcriptional and translational expression of all genes that follow it.

This happens because termination in the first gene can disrupt the production of subsequent proteins encoded by the mRNA.