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Mutations in genes that encode __________ represent the Mutator phenotype.

A. proteins that direct transcription

B. proteins responsible for ligating DNA

C. repair system proteins, or fidelity of replication proteins

D. proteins that participate in recombination and chiasmata formation

User DonQ
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Final answer:

The Mutator phenotype is associated with mutations in genes encoding proteins responsible for DNA repair and maintaining the fidelity of replication. The presence of such mutations can compromise the accuracy of DNA replication and lead to cancer.

Step-by-step explanation:

The question you've asked about the Mutator phenotype refers to mutations in genes that are responsible for the accuracy and integrity of the genetic information during cell division. The correct answer is: C. repair system proteins, or fidelity of replication proteins. These proteins are crucial in ensuring that the DNA is replicated correctly without errors.

Mutations can lead to the development of cancer, as seen in cases where the repair genes are mutated, and they are also responsible for correcting errors that can lead to changes in the amino acid sequence of proteins. For instance, a mutation in the gene encoding for a repair protein like p53 can result in the protein being unable to perform its role in detecting and repairing DNA damage, thereby increasing the risk of cancer.

User TofuMaster
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