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The prokaryotic DNA polymerase IIII holenzyme is help together by which subunit?

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Final answer:

The prokaryotic DNA polymerase III holoenzyme's integrity is maintained by a σ (sigma) subunit, which, combined with the four other core subunits (α, α, β, and β'), constitutes the complete holoenzyme responsible for proper initiation of transcription.

Step-by-step explanation:

The prokaryotic DNA polymerase III holoenzyme is held together by multiple subunits. Essential to this complex is the σ (sigma) subunit, which is involved only in transcription initiation.

The polymerase is composed of five polypeptide subunits, two of which are identical, denoted as α (α), α (α), β (β), and β' (β'), which constitute the core enzyme. The presence of the σ subunit, in addition to these core subunits, forms the complete holoenzyme responsible for initiating the process of transcription accurately.

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