Final answer:
Inheritable innate immune mechanism defects typically lead to a condition called immunodeficiency, which is characterized by the immune system's failure, insufficiency, or delay. Severe combined immunodeficiency disease (SCID) is one of the most serious inherited immunodeficiencies. Acquired immunodeficiencies may also occur, but they are not inherited and can have different causes, such as infection with HIV.
Step-by-step explanation:
People with inheritable innate immune mechanism defects typically experience a condition known as immunodeficiency, which represents a failure, insufficiency, or delay at any level of the immune system. Inherited immunodeficiencies can range from a higher susceptibility to certain infections, such as those caused by some Gram-negative bacteria, to more severe diseases like severe combined immunodeficiency disease (SCID).
These inherited conditions are characterized by an increased susceptibility to infections, and in the case of SCID, both the B cell and T cell arms of the adaptive immune response are affected, resulting in a complex disease caused by different genetic defects.
Examples of other primary immunodeficiencies include chronic granulomatous disease, X-linked agammaglobulinemia, and selective IgA deficiency. While some primary immunodeficiencies become apparent shortly after birth or in early childhood, others may not present symptoms until later in life. On the other hand, there are also acquired immunodeficiencies like HIV, which can have devastating effects on the immune system, but these are not inherited.